2009
- Microscopic marvels: The naked microscope

June 30, 2009
Sunney Xie's newest microscopes don't look like the latest in sophistication. Tucked away in his biochemistry lab at Harvard University, they seem to be ad hoc assemblies of lasers, objectives and electronics, surrounded by a thicket of optical equipment.
- Trimming The Fat Boosts Blood Recovery After Marrow Transplant

June 17, 2009
Seeking ways to improve blood recovery after chemotherapy or bone marrow transplant, researchers at Children's Hospital Boston have discovered that fat cells, which accumulate in bone marrow as people age, inhibit the marrow's ability to produce new blood cells.
- Stem cell protein offers a new cancer target

June 2, 2009
LIN28, which maintains cell 'stemness,' is abundant in advanced cancers and transforms cells to cancerous state.
- First Detailed Report of New Virus's Promiscuous Past

May 26, 2009
The most detailed description yet of the origins of the novel H1N1 virus causing the swine flu outbreak appears today on ScienceExpress.
- Why do people with Down syndrome have less cancer?

May 26, 2009
Research in mice and human stem cells suggests new therapeutic targets.
- Federal Research is Exploring Potential for ‘Human Hibernation’

May 20, 2009
The National Institutes of Health (NIH) has awarded a $2,227,500 grant to explore the possibility of inducing a hibernation-like state in “non-hibernating mammals” such as humans.
- Embryo's Heartbeat Drives Blood Stem Cell Formation

May 13, 2009
Clues about how blood forms could yield new strategies for treating blood diseases.
- Using combinatorial libraries to engineer genetic circuits advances synthetic biology

April 22, 2009
Streamlining the construction of synthetic gene networks has led a team of Boston University researchers to develop a technique that couples libraries of diversified components with computer modeling to guide predictable gene network construction without the back and forth tweaking.
- Study finds blood cells can be reprogrammed to act as embryonic stem cells

April 20, 2009
In a recent study, U.S. researchers have reprogrammed cells found in circulating blood into cells that are molecularly and functionally indistinguishable from embryonic stem cells.
- Penn Scientists Use RNA to Reprogram One Cell Type into Another

April 16, 2009
Implications for Cell-Based Personalized Therapies for Neurodegenerative Diseases.
- Shedding some light on Parkinson's treatment

April 16, 2009
Scientists use optical approach to study deep brain stimulation.
- MIT: Cooperative behavior meshes with evolutionary theory

April 6, 2009
One of the perplexing questions raised by evolutionary theory is how cooperative behavior, which benefits other members of a species at a cost to the individual, came to exist.
- Sleep: Spring cleaning for the brain?

April 2, 2009
If you've ever been sleep-deprived, you know the feeling that your brain is full of wool.
- Stem cell breakthrough: monitoring the on switch that turns stem cells into muscle

April 1, 2009
New report in The FASEB Journal describes how Nobel scientist and colleagues visualize stem cells forming new muscles in a living mouse.
- Penn study finds link between Parkinson's disease genes and manganese poisoning

February 2, 2009
A connection between genetic and environmental causes of Parkinson’s disease has been discovered by a research team led by Aaron D. Gitler, PhD, Assistant Professor in the Department of Cell and Developmental Biology at the University of Pennsylvania School of Medicine.
- Tracking deadly viruses' spread from animals to humans

January 16, 2009
Pandemics can be prevented before they're spread globally, says Dr. Nathan Wolfe.
- Novel technique changes lymph node biopsy, reduces radiation exposure in breast cancer patients

January 13, 2009
Information obtained from a new application of photoacoustic tomography (PAT) is worth its weight in gold to breast cancer patients.
- Wireless Microgrippers Grab Living Cells in 'Biopsy' Tests

January 12, 2009
Johns Hopkins researchers have invented dust-particle-size devices that can be used to grab and remove living cells from hard-to-reach places without the need for electrical wires, tubes or batteries.
- Synthetic HDL: A new weapon to fight cholesterol problems

January 9, 2009
Buttery Christmas cookies, eggnog, juicy beef roast, rich gravy and creamy New York-style cheesecake. Happy holiday food unfortunately can send blood cholesterol levels sky high.
2008
- Science’s Breakthrough of the Year: Reprogramming Cells

December 19, 2008
By inserting genes that turn back a cell's developmental clock, researchers are gaining insights into disease and the biology of how a cell decides its fate.
- Cells’ Protein-Folding ‘ER’ May Play a Role in Type 2 Diabetes

November 24, 2008
“It used to be that for a long time, we thought that type 2 diabetes was just your insulin not working – insulin resistance,” says Feroz Papa, MD, PhD.
- Biomedical Engineers’ Detective Work Reveals Antibiotic Mechanism

November 14, 2008
A series of genetic clues led a team of BU biomedical engineers to uncover exactly how certain antibiotics kill bacteria.
- Nature study demonstrates that bacterial clotting depends on clustering

November 3, 2008
Bacteria shown to cause blood clots.
- Random Event Triggers Cellular Switch

October 20, 2008
A stochastic single-molecule event is enough to switch a bacterial cell from one phenotype to another.
- New prenatal test for Down syndrome less risky than amniocentesis, Stanford/Packard scientists say

October 8, 2008
Pregnant women worried about their babies’ genetic health face a tough decision: get prenatal gene testing and risk miscarriage, or skip the tests and miss the chance to learn of genetic defects before birth.
- Important new step toward producing stem cells for human treatment

September 25, 2008
Harvard researchers produce iPS cells without use of retroviruses.
- New Protein Structure Could Spur Research on Metabolism, Cell Death

September 4, 2008
Researchers have determined the structure of a human membrane protein involved in metabolism and the self-destruction of cells.
- Infections linked to premature births more common than thought, Stanford study finds

August 25, 2008
Previously unrecognized and unidentified infections of amniotic fluid may be a significant cause of premature birth, according to researchers at the Stanford University School of Medicine.
- Amplifying Small Molecules

August 14, 2008
Supramolecular complex generates target compounds in PCR-like cascade reaction.
- Daley and colleagues create 20 disease-specific stem cell lines

August 7, 2008
Lines to be part of new HSCI iPS collection available to researchers.
- Scientists discover the travel patterns of seasonal flu

April 16, 2008
Scientists discover the travel patterns of seasonal flu – findings may lead to improved flu vaccines.
- Scientists Identify New Leads for Treating Parasitic Worm Disease
March 16, 2008
Compounds May Provide Much-Needed New Weapons In Worldwide Battle Against Schistosomiasis.
- Bird brains suggest how vocal learning evolved

March 11, 2008
Though they perch far apart on the avian family tree, birds with the ability to learn songs use similar brain structures to sing their tunes.
- Regulator of microRNAs is key to cell reprogramming and carcinogenesis

February 21, 2008
MicroRNAs are a recently discovered class of RNAs that encode no proteins but instead regulate gene activity.
- DNA is blueprint, contractor and construction worker for new structures

January 31, 2008
DNA is the blueprint of all life, giving instruction and function to organisms ranging from simple one-celled bacteria to complex human beings.
- Team IDs weakness in anthrax bacteria

January 22, 2008
MIT and New York University researchers have identified a weakness in the defenses of the anthrax bacterium that could be exploited to produce new antibiotics.
- Study: Brain connections strengthen during waking hours, weaken during sleep

January 20, 2008
Most people know it from experience: After so many hours of being awake, your brain feels unable to absorb any more—and several hours of sleep will refresh it.
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