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2009
- Imaging study shows brain abnormalities in chemotherapy patients

November 11, 2009
Researchers at Stanford University School of Medicine have used neuroimaging to gain insight into a phenomenon known as “chemo brain,” a condition in which cancer patients have difficulty thinking, focusing and remembering.
- An exquisite container

November 3, 2009
A tiny cage of gold covered with a smart polymer respond to light, opening to empty its contents.
- Harvard scientists bend nanowires into 2-D and 3-D structures

October 21, 2009
New ‘stereocenters’ introduce triangular joints into otherwise linear nanomaterials
- PSA 'Nanotest' May Spot Prostate Cancer's Return After Surgery

October 19, 2009
Screen could boost accuracy but is still years away from approval, experts say.
- Stretching the Golgi: a link between form and function

October 15, 2009
A research team at the University of California, San Diego School of Medicine has provided a surprisingly simple explanation for the mechanism and features of the “Golgi apparatus”—a structure that has baffled generations of scientists.
- Using Simple Genome, Columbia Researchers Move Personalized Medicine Closer to Reality

October 13, 2009
Researchers at Columbia University have developed a statistical method that accurately predicts how an organism will respond to dozens of commonly used drugs.
- Nanotech Researchers Develop Artificial Pore

September 28, 2009
Using an RNA-powered nanomotor, University of Cincinnati (UC) biomedical engineering researchers have successfully developed an artificial pore able to transmit nanoscale material through a membrane.
- Gene action partially explains treatment success in newborn lungs

September 23, 2009
For more than a decade, obstetrician-gynecologists have given pregnant women facing premature birth steroids to hasten the development of their newborn's lungs. Now a study appearing online in the Proceedings of the National Academy of Sciences involving a "mystery" gene called Erk3 explains the success of that therapy.
- With A Flash Of Light, A Neuron's Function Is Revealed

September 16, 2009
There’s a new way to explore biology’s secrets. With a flash of light, scientists from the U.S. Department of Energy’s Lawrence Berkeley National Laboratory and the University of California, Berkeley zeroed in on the type of neural cell that controls swimming in larval zebrafish.
- UCSF researchers program cells to be remote-controlled by light

September 13, 2009
UCSF researchers have genetically encoded mouse cells to respond to light, creating cells that can be trained to follow a light beam or stop on command like microscopic robots.
- High fat diet in pregnancy changes metabolome of mother, offspring

September 4, 2009
A high fat diet during pregnancy not only results in offspring with fatty livers, but actually changes the small molecules that govern metabolism, said a consortium of researchers led by those from Baylor College of Medicine in a report that appears in the current issue of the American Journal of Obstetrics and Gynecology.
- Large-scale study probes how cells fight pathogens

September 3, 2009
Researchers reconstruct a key molecular circuit in mammalian immune cells; genome-scale methods offer a practical model for future studies.
- Cost of Decoding a Genome Is Lowered

August 11, 2009
A Stanford engineer has invented a new technology for decoding DNA and used it to decode his own genome for less than $50,000.
- UCSB Study Links Strength and Beauty to Anger, Pro-War Attitudes

August 5, 2009
Anthropologists, psychologists, and other experts in human behavior have long recognized anger as a universal emotion.
- Scientists Discover Origin of Malaria (PDF, 2 pages)

August 3, 2009
Discovery Could Lead to Development of New Treatments, Prevent Future Plagues.
- Higher drug doses needed to defeat tuberculosis, researchers report

July 30, 2009
The typical dose of a medication considered pivotal in treating tuberculosis effectively is much too low to account for modern-day physiques, UT Southwestern Medical Center researchers said.
- A matter of density, not quantity

July 10, 2009
Individual bacterial cells are capable of quorum sensing when confined in small volumes.
- Research may hold key to maintaining embryonic stem cells in lab

July 9, 2009
In a new study that could transform embryonic stem cell (ES cell) research, scientists at UT Southwestern Medical Center have discovered why mouse ES cells can be easily grown in a laboratory while other mammalian ES cells are difficult, if not impossible, to maintain.
- Stem cells’ “suspended” state preserved by key step, scientists report

July 9, 2009
Scientists have identified a gene that is essential for embryonic stem cells to maintain their all-purpose, pluripotent state.
- Microscopic marvels: The naked microscope

June 30, 2009
Sunney Xie's newest microscopes don't look like the latest in sophistication. Tucked away in his biochemistry lab at Harvard University, they seem to be ad hoc assemblies of lasers, objectives and electronics, surrounded by a thicket of optical equipment.
- Trimming The Fat Boosts Blood Recovery After Marrow Transplant

June 17, 2009
Seeking ways to improve blood recovery after chemotherapy or bone marrow transplant, researchers at Children's Hospital Boston have discovered that fat cells, which accumulate in bone marrow as people age, inhibit the marrow's ability to produce new blood cells.
- Stem cell protein offers a new cancer target

June 2, 2009
LIN28, which maintains cell 'stemness,' is abundant in advanced cancers and transforms cells to cancerous state.
- First Detailed Report of New Virus's Promiscuous Past

May 26, 2009
The most detailed description yet of the origins of the novel H1N1 virus causing the swine flu outbreak appears today on ScienceExpress.
- Why do people with Down syndrome have less cancer?

May 26, 2009
Research in mice and human stem cells suggests new therapeutic targets.
- Federal Research is Exploring Potential for ‘Human Hibernation’

May 20, 2009
The National Institutes of Health (NIH) has awarded a $2,227,500 grant to explore the possibility of inducing a hibernation-like state in “non-hibernating mammals” such as humans.
- Embryo's Heartbeat Drives Blood Stem Cell Formation

May 13, 2009
Clues about how blood forms could yield new strategies for treating blood diseases.
- Using combinatorial libraries to engineer genetic circuits advances synthetic biology

April 22, 2009
Streamlining the construction of synthetic gene networks has led a team of Boston University researchers to develop a technique that couples libraries of diversified components with computer modeling to guide predictable gene network construction without the back and forth tweaking.
- Study finds blood cells can be reprogrammed to act as embryonic stem cells

April 20, 2009
In a recent study, U.S. researchers have reprogrammed cells found in circulating blood into cells that are molecularly and functionally indistinguishable from embryonic stem cells.
- Penn Scientists Use RNA to Reprogram One Cell Type into Another

April 16, 2009
Implications for Cell-Based Personalized Therapies for Neurodegenerative Diseases.
- Shedding some light on Parkinson's treatment

April 16, 2009
Scientists use optical approach to study deep brain stimulation.
- MIT: Cooperative behavior meshes with evolutionary theory

April 6, 2009
One of the perplexing questions raised by evolutionary theory is how cooperative behavior, which benefits other members of a species at a cost to the individual, came to exist.
- Sleep: Spring cleaning for the brain?

April 2, 2009
If you've ever been sleep-deprived, you know the feeling that your brain is full of wool.
- Stem cell breakthrough: monitoring the on switch that turns stem cells into muscle

April 1, 2009
New report in The FASEB Journal describes how Nobel scientist and colleagues visualize stem cells forming new muscles in a living mouse.
- Scripps Research Scientists Find Structure of a Protein that Makes Cancer Cells Resistant to Chemotherapy

March 25, 2009
A research team at the Scripps Research Institute has obtained the first glimpse of a protein that keeps certain substances, including many drugs, out of cells.
- Malaria parasite zeroes in on molecule to enhance its survival, team finds

February 19, 2009
A team of researchers from Princeton University and the Drexel University College of Medicine has found that the parasite that causes malaria breaks down an important amino acid in its quest to adapt and thrive within the human body.
- Penn study finds link between Parkinson's disease genes and manganese poisoning

February 2, 2009
A connection between genetic and environmental causes of Parkinson’s disease has been discovered by a research team led by Aaron D. Gitler, PhD, Assistant Professor in the Department of Cell and Developmental Biology at the University of Pennsylvania School of Medicine.
- Tracking deadly viruses' spread from animals to humans

January 16, 2009
Pandemics can be prevented before they're spread globally, says Dr. Nathan Wolfe.
- Novel technique changes lymph node biopsy, reduces radiation exposure in breast cancer patients

January 13, 2009
Information obtained from a new application of photoacoustic tomography (PAT) is worth its weight in gold to breast cancer patients.
- Wireless Microgrippers Grab Living Cells in 'Biopsy' Tests

January 12, 2009
Johns Hopkins researchers have invented dust-particle-size devices that can be used to grab and remove living cells from hard-to-reach places without the need for electrical wires, tubes or batteries.
- Synthetic HDL: A new weapon to fight cholesterol problems

January 9, 2009
Buttery Christmas cookies, eggnog, juicy beef roast, rich gravy and creamy New York-style cheesecake. Happy holiday food unfortunately can send blood cholesterol levels sky high.
2008
- Science’s Breakthrough of the Year: Reprogramming Cells

December 19, 2008
By inserting genes that turn back a cell's developmental clock, researchers are gaining insights into disease and the biology of how a cell decides its fate.
- Cells’ Protein-Folding ‘ER’ May Play a Role in Type 2 Diabetes

November 24, 2008
“It used to be that for a long time, we thought that type 2 diabetes was just your insulin not working – insulin resistance,” says Feroz Papa, MD, PhD.
- Biomedical Engineers’ Detective Work Reveals Antibiotic Mechanism

November 14, 2008
A series of genetic clues led a team of BU biomedical engineers to uncover exactly how certain antibiotics kill bacteria.
- Nature study demonstrates that bacterial clotting depends on clustering

November 3, 2008
Bacteria shown to cause blood clots.
- Random Event Triggers Cellular Switch

October 20, 2008
A stochastic single-molecule event is enough to switch a bacterial cell from one phenotype to another.
- New prenatal test for Down syndrome less risky than amniocentesis, Stanford/Packard scientists say

October 8, 2008
Pregnant women worried about their babies’ genetic health face a tough decision: get prenatal gene testing and risk miscarriage, or skip the tests and miss the chance to learn of genetic defects before birth.
- Important new step toward producing stem cells for human treatment

September 25, 2008
Harvard researchers produce iPS cells without use of retroviruses.
- New Protein Structure Could Spur Research on Metabolism, Cell Death

September 4, 2008
Researchers have determined the structure of a human membrane protein involved in metabolism and the self-destruction of cells.
- Infections linked to premature births more common than thought, Stanford study finds

August 25, 2008
Previously unrecognized and unidentified infections of amniotic fluid may be a significant cause of premature birth, according to researchers at the Stanford University School of Medicine.
- Amplifying Small Molecules

August 14, 2008
Supramolecular complex generates target compounds in PCR-like cascade reaction.
- Daley and colleagues create 20 disease-specific stem cell lines

August 7, 2008
Lines to be part of new HSCI iPS collection available to researchers.
- Scientists discover the travel patterns of seasonal flu

April 16, 2008
Scientists discover the travel patterns of seasonal flu – findings may lead to improved flu vaccines.
- Scientists Identify New Leads for Treating Parasitic Worm Disease
March 16, 2008
Compounds May Provide Much-Needed New Weapons In Worldwide Battle Against Schistosomiasis.
- Bird brains suggest how vocal learning evolved

March 11, 2008
Though they perch far apart on the avian family tree, birds with the ability to learn songs use similar brain structures to sing their tunes.
- Regulator of microRNAs is key to cell reprogramming and carcinogenesis

February 21, 2008
MicroRNAs are a recently discovered class of RNAs that encode no proteins but instead regulate gene activity.
- DNA is blueprint, contractor and construction worker for new structures

January 31, 2008
DNA is the blueprint of all life, giving instruction and function to organisms ranging from simple one-celled bacteria to complex human beings.
- Team IDs weakness in anthrax bacteria

January 22, 2008
MIT and New York University researchers have identified a weakness in the defenses of the anthrax bacterium that could be exploited to produce new antibiotics.
- Study: Brain connections strengthen during waking hours, weaken during sleep

January 20, 2008
Most people know it from experience: After so many hours of being awake, your brain feels unable to absorb any more—and several hours of sleep will refresh it.
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