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Science News About New Innovator Awardees
- Stretching the Golgi: a link between form and function

October 15, 2009
A research team at the University of California, San Diego School of Medicine has provided a surprisingly simple explanation for the mechanism and features of the “Golgi apparatus”—a structure that has baffled generations of scientists.
- Using Simple Genome, Columbia Researchers Move Personalized Medicine Closer to Reality

October 13, 2009
Researchers at Columbia University have developed a statistical method that accurately predicts how an organism will respond to dozens of commonly used drugs.
- Gene action partially explains treatment success in newborn lungs

September 23, 2009
For more than a decade, obstetrician-gynecologists have given pregnant women facing premature birth steroids to hasten the development of their newborn's lungs. Now a study appearing online in the Proceedings of the National Academy of Sciences involving a "mystery" gene called Erk3 explains the success of that therapy.
- High fat diet in pregnancy changes metabolome of mother, offspring

September 4, 2009
A high fat diet during pregnancy not only results in offspring with fatty livers, but actually changes the small molecules that govern metabolism, said a consortium of researchers led by those from Baylor College of Medicine in a report that appears in the current issue of the American Journal of Obstetrics and Gynecology.
- Large-scale study probes how cells fight pathogens

September 3, 2009
Researchers reconstruct a key molecular circuit in mammalian immune cells; genome-scale methods offer a practical model for future studies.
- Higher drug doses needed to defeat tuberculosis, researchers report

July 30, 2009
The typical dose of a medication considered pivotal in treating tuberculosis effectively is much too low to account for modern-day physiques, UT Southwestern Medical Center researchers said.
- Stem cells’ “suspended” state preserved by key step, scientists report

July 9, 2009
Scientists have identified a gene that is essential for embryonic stem cells to maintain their all-purpose, pluripotent state.
- Konrad Hochedlinger: A reprogramming revolutionary

July 7, 2009
In 1999, Konrad Hochedlinger squeezed into a packed lecture at the Institute of Molecular Pathology in Vienna to hear stem cell researcher Rudolf Jaenisch talk about nuclear transfer cloning techniques.
- Ed Boyden: The brain engineer

March 3, 2009
At the end of his junior year at the Massachusetts Institute of Technology in 1998, Ed Boyden was hanging out with friends in the basement of the famed Media Lab, trying to figure out what to do for the summer.
- Malaria parasite zeroes in on molecule to enhance its survival, team finds

February 19, 2009
A team of researchers from Princeton University and the Drexel University College of Medicine has found that the parasite that causes malaria breaks down an important amino acid in its quest to adapt and thrive within the human body.
- Penn study finds link between Parkinson's disease genes and manganese poisoning

February 2, 2009
A connection between genetic and environmental causes of Parkinson’s disease has been discovered by a research team led by Aaron D. Gitler, PhD, Assistant Professor in the Department of Cell and Developmental Biology at the University of Pennsylvania School of Medicine.
- Wireless Microgrippers Grab Living Cells in 'Biopsy' Tests

January 12, 2009
Johns Hopkins researchers have invented dust-particle-size devices that can be used to grab and remove living cells from hard-to-reach places without the need for electrical wires, tubes or batteries.
- Science’s Breakthrough of the Year: Reprogramming Cells

December 19, 2008
By inserting genes that turn back a cell's developmental clock, researchers are gaining insights into disease and the biology of how a cell decides its fate.
- Cells’ Protein-Folding ‘ER’ May Play a Role in Type 2 Diabetes

November 24, 2008
“It used to be that for a long time, we thought that type 2 diabetes was just your insulin not working – insulin resistance,” says Feroz Papa, MD, PhD.
- Important new step toward producing stem cells for human treatment

September 25, 2008
Harvard researchers produce iPS cells without use of retroviruses.
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