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Agenda
For additional information about the Workshop, please contact either Cristen Robinson or Anna Rossoshek at GTEXInfo@mail.nih.gov.
| Day 1: June 2, Monday |
| 8:00 a.m. |
Continental Breakfast |
| 8:30 a.m. |
Francis Collins: Welcome and Introduction to Aims of GTEx Proposal |
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Overview Talks |
| 9:00 a.m. |
GWAS studies, eQTLs, and Beyond
Cliona Molony
John Hardy
Discussion |
| 10:00 a.m. |
Coffee Break |
| 10:30 a.m. |
Challenges of Obtaining Multiple, High-Quality Tissues for GTEx
Carolyn Compton
Mark Rubin
John Lonsdale
Discussion |
| 11:30 a.m. |
Lunch |
| 12:30 p.m. |
Consideration of Ethical, Legal, and Social Implications (ELSI)
Stuart Youngner
Laura Beskow
Discussion |
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Breakout Sessions
Most groups will be run twice, with different leaders and a different mix of people. Each group/session has an assigned note-taker and assigned leader. ELSI will be integrated into all group discussions. |
| 1:30 p.m. |
Breakout Session I
Group A: Statistical/Epidemiology Issues; Size, Statistical Power, Phenotypic Variables, Analytical Plans (Group Leaders: Nancy Cox, Manolis Detmitzakis, Richard Spielman)
Group B: Building a Public Database of eQTL Data: Access and Analytical Tools (Group Leader: Ron Edgar)
Group C: Procuring Tissues of High Quality: Setting Quality Standards (Group Leader: Ron Zielke)
Group D: Laboratory Analysis of Tissues for Global RNA Expression: Methods and Quality Standards (Group Leaders: Martin Hirst) |
| 3:00 p.m. |
Coffee Break |
| 3:30 p.m. |
Breakout Session II: (Most participants from Session I will join different groups in Session II.)
Group A: Break into 2-3 sub-groups based on discussion during Session I
• A1 sub-topic to be determined in Session I (Nancy Cox)
• A2 sub-topic to be determined in Session I (Manolis Dermitzakis)
• A3 sub-topic to be determined in Session I (Richard Spielman)
Group C: Procuring Tissues of High Quality: Setting Quality Standards (Group Leader: Mark Sobel)
Group D: Laboratory Analysis of Tissues for Global RNA Expression: Methods and Quality Standards (Group Leader: John Walker) |
| 5:00 p.m. |
Group Leaders and Scribes Review and Consolidate Notes |
| 6:00 p.m. |
Meet and Greet (Atrium) |
| Day 2: Tuesday, June 3 |
| 8:00 a.m. |
Continental Breakfast |
| 8:30 a.m. |
Summarizing Results of Breakout Sessions |
| 8:30 a.m. |
Group A Leaders |
| 9:00 a.m. |
Group B Leaders |
| 10:00 a.m. |
Coffee Break |
| 10:15 a.m. |
Group C Leaders |
| 11:15 a.m. |
Group D Leaders |
| 12 noon |
Lunch |
| 1:30 p.m. |
Drafting Recommendations for GTEx Proposal (30 minutes each)
Chair: Francis Collins
• Statistical/Epidemiology Issues
• Public Database
• Tissue Procurement
• ELSI Considerations
• Data Quality Standards
• Laboratory Analyses |
| 3:30 p.m. |
End of Workshop |
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